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Place of Origin:      Hunan,China

Brand Name:          Kang

Model Number:      KL-007

Certification:          ISO9001/Halal/Kosher

CAS No.:                 10236-47-2

Molecule formula:  C27H32O14

Product Commercial Terms
Minimum Order Quantity:1KG
Packaging Details:Paper drum with double inner food-grade pe bag
Delivery Time:7-15 days
Payment Terms:T/T;L/C;Western Union
Supply Ability:100 MT per year
Quick Detail:

1. Description

Naringin is extracted from grapefruit fruit. It's a compound capable of exerting many health benefits and helpful in preventing and treating many conditions and illnesses.

This bioflavonoid has antioxidant and antifungal properties, and as such may help prevent cancer and atherosclerosis (hardening of arteries), as well as a few other ailments.
Naringin also works synergistically with other nutrients, increasing the bio-availability and therefore maximizing the health benefits of these nutrients.

It could be used as bitter agent in beer and coffee, and formulas containing large percentage of sugar.

2. Specifications

Basic InformationProduct NameNaringin
Botanical SourceCitrus grandis
CAS NO10236-47-2
AppearanceFormFine powder
Physical / Chemical charactersMolecule formulaC27H32O14
Molecule weight580.53
SolubilityHardly dissolve in cold water, partially soluble in hot water, methanol, ethanol
PurityNaringin ( on dry basis )96%-98% HPLC
Melting point247-250℃
Residue on ignition≤0.5%
Lead (Pb)≤2mg/kg
MicrobiologicalTotal plate count≤1000 CFU/g
Molds & yeast≤100 CFU/g
E.coliNegative / 25g
Pathogenic bacteria (shigella, salmonella, staphylococcus aureus, hemolytic streptococcus)Negative / 25g
Package StorageSealed in 25 kg paper drum, with double inner food-grade plastic bag, drum size: 40*40*50CM. Stored in cool and dry space, avoid strong direct heat and light.
Shelf life24 months
Legal statusComply with the British Pharmacopoeia Volume V Appendices
Appendix I A. General Reagents Naringin, the EDQM (EP7.0 4.1.1 Reagents N.443 )
Non-GMO and radiationProduction of Non-GMO raw materials, and no ionizing radiation.
CertificatesISO22000, ISO9001, Kosher, Halal

3. Functions and Features

Antioxidant effect

Naringin was shown to possessstrong superoxide scavenging activity and xanthine oxidase inhibitory activity, andthe ability to quenchROS, decrease the oxygen-free radical-stimulated K+ permeability, and inhibit lipid peroxidation.

● Anti-inflammatory effect

Naringin has been shown to mediate its anti-inflammatory effect by inhibiting IL-8, MCP-1, and MIP-1α secretion and mRNA expression, and by inhibiting the phosphorylation of ERK1/2, JNK, and p38 MAPK, probably through blocking the activation of the NF-κB and MAPK signaling pathways.

● Cardioprotective effects:potentially retard the progression of atherosclerosis

● Neuroprotection:beneficial effect in alleviation of Alzheimerʼs disease

● Bone diseases:augmented osteoblastic activity; improve osteogenic proliferation and differentiation in MC3T3-E1 cells; prevent bone loss

● Gastrointestinal tract:reduced the ulcer index and improved gastric mucosal morphology

4. Applications

● Applied in pharmaceutical field, in the form of tablet or capsule, for provention or alleviation of  atherosclerosis, Alzheimerʼs, gastrointestinal disorder, or bone loss.

● Applied in food and drink industries, as bitter agent or taste modifier.

● Applied in cosmetic products, for skin nourishing or redness alleviation.

● As raw material for preparation of dihydrochalcone sweeteners like neohesperidin DC(NHDC) and naringin DC(NADC).

5. Packing Delivery

Bulk package(10kg-25kg): Paper drum with double inner food-grade pe bag.

Small package(1kg-5kg): Aluminum foil bag with inner food-grade pe bag (or as required).


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